Open AccessIsolation, Semi-Synthesis and Antifeedant Activity of Constituents from Derris scandens Benth.
Author(s) -
P. Poorna,
K. Ramakrishna,
Ming Rao
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2020.22801
Subject(s) - chemistry , bioassay , chloroform , traditional medicine , isolation (microbiology) , chromatography , biology , microbiology and biotechnology , medicine , genetics
This work describes the semi-synthesis of derivatives from derris isoflavone-A (1), scandenin (2) and6,8-diprenyl-4′,5,7-trihydroxy isoflavone (3) which are major constituents isolated from chloroformextract of Derris scandens Benth. All the semi-synthesized derivatives (4-11) were characterized byNMR and mass spectroscopic techniques. All these derivatives are evaluated for their antifeedantactivity in castor semilooper and tobacco caterpillar using a no-choice laboratory bioassay. The resultsdemonstrated that scandenin (2), compounds 5, 7 and 10 have shown potent insecticidal activity.