Open AccessOne-Pot, Water-Mediated, H2O2-HCl Catalyzed Synthesis of Benzazepines
Author(s) -
Nidhi Singh,
Jaya Pandey
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2020.22574
Subject(s) - benzazepines , chemistry , catalysis , ketone , benzazepine , combinatorial chemistry , organic chemistry
One-pot, multicomponent H2O2-HCl catalyzed system was employed for the synthesis of a series ofbenzazepine compounds. The implemented procedure oxidized the carbon-nitrogen bonds and producedbenzazepines, while integrating diamines and substituted ketone. The advantage of the exercisedsynthetic route was that the reaction was water mediated and the completion time was quite reducedcompared to the time required by conventional methods