Open AccessSynthesis of Novel Nitric Oxide Releasing Furoxan Hybrids from Biologically Active Bicyclic Amine and their Antioxidant Activity
Author(s) -
Prabhuling M. Swami,
P. K. Zubaidha,
Girdharilal B. Tiwari
Publication year - 2019
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2019.21948
Subject(s) - chemistry , antioxidant , furoxan , nitric oxide , ascorbic acid , dpph , amine gas treating , bicyclic molecule , organic chemistry , nitric acid , combinatorial chemistry , food science
The present paper describes the synthesis of novel nitric oxide hybrids obtained by linking bioactive bicyclic amine to substituted furoxans. The antioxidant activities were studied in vitro based on the radical scavenging effect of stable DPPH free radical using ascorbic acid as a standard. The nitric oxide hybrids showed remarkable antioxidant properties and hence, can be employed as potential antioxidant agents.