Use of animal models for testing drugs targeting osteoarthritis symptoms and articular tissue structural changes

targets, as well as being required by the regulatory agencies for pharmacokinetics and pharmaco-toxicological studies. For pain study, it is generally felt that naturally occurring models may be better than surgically induced models. Conclusion Experimental animal models of Osteoarthritis are of high interest as their use can help to provide insight into the disease process and evaluate therapeutic agents that may be effective in humans.