Open AccessFGFR2-TSC22D1, a novel FGFR2 fusion gene identified in a patient with colorectal cancer: A case report
Author(s) -
Xiaoming Kao,
Xi Zhu,
Junling Zhang,
Shi-Qing Chen,
Caibin Fan
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i23.6867
Subject(s) - medicine , colorectal cancer , fusion gene , gene , cancer , oncology , genetics , biology
The FGFR signaling pathway is activated in multiple tumor types through gene amplifications, single base substitutions, or gene fusions. Novel FGFR gene fusions may represent candidate targets for the development of tyrosine kinase inhibitors.