Open AccessDiagnostic and prognostic value of secreted protein acidic and rich in cysteine in the diffuse large B-cell lymphoma
Author(s) -
Peng-Ji Pan,
Junxia Liu
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i22.6287
Subject(s) - medicine , diffuse large b cell lymphoma , cysteine , lymphoma , value (mathematics) , pathology , radiology , biochemistry , enzyme , chemistry , machine learning , computer science
Secreted protein acidic and rich in cysteine (SPARC) is an extracellular matrix-associated protein. Studies have revealed that SPARC is involved in the cell interaction and function including proliferation, differentiation, and apoptosis. However, the role of SPARC in cancer is controversial, as it was reported as the promoter or suppressor in different cancers. Further, the role of SPARC in lymphoma is unclear.