Open AccessMacrophage activation syndrome as an initial presentation of systemic lupus erythematosus
Author(s) -
Lianjie Shi,
Qian Guo,
Shengguang Li
Publication year - 2020
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v8.i11.2406
Subject(s) - medicine , macrophage activation syndrome , macrophage , presentation (obstetrics) , systemic lupus erythematosus , dermatology , lupus erythematosus , immunology , surgery , arthritis , disease , antibody , biochemistry , chemistry , in vitro
In a recent article on World J Clin Cases 2019; 7: 3859-3865, Sun et al reported a case of 36-year-old female with macrophage activity syndrome as an onset of systemic lupus erythematosus. Although this is a very interesting case, some concerns still need to be addressed. First, the patient had an extremely elevated serum ferritin but a normal C-reactive protein level, which was unparallel with the inflammatory condition before she received any treatments. Second, the diagnosis of systemic lupus erythematosus seemed to be insufficient according to the patient's medical information presented, most of which were not specific to lupus but could be explained by macrophage activity syndrome. Hence, more medical information on the patient should be provided, and a profound discussion needs to be addressed.