Open AccessNext generation sequencing reveals co-existence of hereditary spherocytosis and Dubin–Johnson syndrome in a Chinese gril: A case report
Author(s) -
Yuan Li,
Yang Li,
Yang Yang,
Wenrui Yang,
Jianping Li,
Guangxin Peng,
Lin Song,
Huihui Fan,
Lei Ye,
Yuanyuan Xiong,
Zhijie Wu,
Kang Zhou,
Xin Zhao,
Liping Jing,
Fengkui Zhang,
Li Zhang
Publication year - 2019
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v7.i20.3303
Subject(s) - hereditary spherocytosis , medicine , jaundice , bilirubin , ursodeoxycholic acid , hemolytic anemia , spherocytosis , gastroenterology , anemia , pediatrics , splenectomy , spleen
Hereditary spherocytosis (HS) is a hereditary disease of hemolytic anemia that occurs due to the erythrocyte membrane defects. Dubin-Johnson syndrome (DJS), which commonly results in jaundice, is a benign hereditary disorder of bilirubin clearance that occurs only rarely. The co-occurrence of HS and DJS is extremely rare. We recently diagnosed and treated a case of co-occurring HS and DJS.