Open AccessCytokine release syndrome complicated with rhabdomyolysis after chimeric antigen receptor T-cell therapy: A case report
Author(s) -
Lan Zhang,
Wei Chen,
Xiaomin Wang,
Shuqing Zhang
Publication year - 2022
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v10.i26.9398
Subject(s) - medicine , cytokine release syndrome , rhabdomyolysis , myalgia , chimeric antigen receptor , tocilizumab , gastroenterology , immunology , immunotherapy , immune system , disease
Chimeric antigen receptor T-Cell (CAR-T) therapy is an effective new treatment for hematologic malignancies. Cytokine release syndrome (CRS) and neurologic toxicity are main toxicities. CRS-induced rhabdomyolysis (RM) followed by CAR-T therapy treatment has not been previously reported.