Open AccessEarly detection of circulating tumor DNA and successful treatment with osimertinib in thr790met-positive leptomeningeal metastatic lung cancer: A case report
Author(s) -
Liguang Xu,
Yingjin Wang,
Shengli Shen,
Yao Wu,
Hongzhou Duan
Publication year - 2022
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v10.i22.7968
Subject(s) - medicine , osimertinib , lung cancer , epidermal growth factor receptor , liquid biopsy , gefitinib , adenocarcinoma , cerebrospinal fluid , oncology , brain metastasis , metastasis , pathology , cancer , biopsy , erlotinib
Patients diagnosed with non-small-cell lung cancer with activated epidermal growth factor receptor mutations are more likely to develop leptomeningeal (LM) metastasis than other types of lung cancers and have a poor prognosis. Early diagnosis and effective treatment of leptomeningeal carcinoma can improve the prognosis.