Open AccessHematopoiesis reconstitution and anti-tumor effectiveness of Pai-Neng-Da capsule in acute leukemia patients with haploidentical hematopoietic stem cell transplantation
Author(s) -
Jiaojiao Yuan,
Ying Lü,
Junjie Cao,
Renzhi Pei,
Ruilan Gao
Publication year - 2022
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v10.i14.4425
Subject(s) - medicine , hematopoietic stem cell transplantation , acute leukemia , haematopoiesis , transplantation , capsule , gastroenterology , leukemia , stem cell , cd34 , complication , oncology , surgery , botany , biology , genetics
With the rapid development of haploidentical hematopoietic stem cell transplantation (haplo-HSCT), primary poor graft function (PGF) has become a life-threatening complication. Effective therapies for PGF are inconclusive. New Chinese patent medicine Pai-Neng-Da (PND) Capsule exerts dual effect in promoting hematopoiesis recovery and regulating immunity. Still, the application of PND capsule in hematopoietic stem cell transplantation, especially in the haplo-HSCT setting, has not yet been reported.