Dysfunctional Subcutaneous Fat With Reduced Dicer and Brown Adipose Tissue Gene Expression in HIV-Infected Patients
Author(s) -
Martin Torriani,
Suman Srinivasa,
Kathleen V. Fitch,
Thomas Thomou,
Kimberly Wong,
Eva Petrow,
C. Ronald Kahn,
Aaron M. Cypess,
Steven Grinspoon
Publication year - 2016
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-3993
Subject(s) - prdm16 , adipose tissue , endocrinology , medicine , white adipose tissue , dicer , adipocyte , leptin , biology , obesity , gene , genetics , small interfering rna , transfection
HIV patients are at an increased risk for cardiometabolic disease secondary to depot-specific alterations in adipose function, but mechanisms remain poorly understood.
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