Open AccessFunctional Analyses of Melanocortin-4 Receptor Mutations Identified from Patients with Binge Eating Disorder and Nonobese or Obese Subjects
Author(s) -
YaXiong Tao,
Deborah L. Segaloff
Publication year - 2005
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-0519
Subject(s) - melanocortin 4 receptor , loss function , phenotype , penetrance , context (archaeology) , obesity , weight loss , melanocortin , medicine , biology , endocrinology , binge eating , genetics , receptor , gene , paleontology
Whether mutations in the melanocortin-4 receptor (MC4R) are the cause of binge eating disorder was controversial. In addition, the penetrance of mutations in the MC4R in causing obesity was debated.
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