Methodological Issues in Estrogen Treatment Trials for Alzheimer's Disease | Zendy

MULNARD RUTH A. | Zendy

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Methodological Issues in Estrogen Treatment Trials for Alzheimer's Disease

Author(s) -

MULNARD RUTH A.

Publication year - 2005

Publication title -

annals of the new york academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.712

H-Index - 248

eISSN - 1749-6632

pISSN - 0077-8923

DOI - 10.1196/annals.1347.014

Subject(s) - estrogen , disease , clinical trial , medicine , alzheimer's disease , estrogen replacement therapy , bioinformatics , intensive care medicine , biology

A bstract : Over the past two decades, many clinical trials have been conducted using different forms of estrogen therapy with and without progestin supplementation in an effort to treat diagnosed Alzheimer's disease. Design variations among these trials may account for the inconsistent results of these investigations and the persistent gap in knowledge about the appropriate use of estrogen in the treatment paradigm for degenerative diseases.

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