Characterization of Antiapoptotic Activities of  Chlamydia pneumoniae  in Infected Cells | Zendy

Fischer S F. | Zendy; Häcker G | Zendy

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Characterization of Antiapoptotic Activities of Chlamydia pneumoniae in Infected Cells

Author(s) -

Fischer S F.,

Häcker G

Publication year - 2003

Publication title -

annals of the new york academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.712

H-Index - 248

eISSN - 1749-6632

pISSN - 0077-8923

DOI - 10.1196/annals.1299.105

Subject(s) - apoptosis , signal transduction , microbiology and biotechnology , transduction (biophysics) , cell , biology , chemistry , biochemistry

A bstract :C. pneumoniae has the capacity to inhibit apoptosis. Here we provide further insight into how infection with C. pneumoniae affects the apoptotic signal transduction in infected human epitheloid cells. For assessing changes in the apoptotic response, intact cells and cell extracts were used. These results show that C. pneumoniae is able to interfere with the host cell's apoptotic apparatus at least at two steps in the signal transduction.

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