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mTOR inhibition potentiates cytotoxicity of Vγ4 γδ T cells via up‐regulating NKG2D and TNF‐α
Author(s) -
Cao Guangchao,
Wang Qian,
Li Guangqiang,
Meng Ziyu,
Liu Hui,
Tong Jiyu,
Huang Wanjun,
Liu Zonghua,
Jia Yanqiong,
Wei Jun,
Chi Hongbo,
Yang Hengwen,
Zhao Liqing,
Wu Zhenzhou,
Hao Jianlei,
Yin Zhinan
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.5a0116-053rr
Subject(s) - cytotoxic t cell , nkg2d , biology , pi3k/akt/mtor pathway , cytotoxicity , cancer research , microbiology and biotechnology , t cell , immune system , signal transduction , immunology , in vitro , biochemistry
Strategy to improve γδ T cells based cancer immunotherapy by suppressing mTOR signaling.