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Perforin‐2/Mpeg1 and other pore‐forming proteins throughout evolution
Author(s) -
McCormack Ryan,
Podack Eckhard R.
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4mr1114-523rr
Subject(s) - perforin , biology , complement membrane attack complex , microbiology and biotechnology , innate immune system , immune system , complement system , effector , immunology , cd8
Review of how Perforin‐2/Mpeg1 is highly conserved from Porifera to modern vertebrates, assisting the innate immune system in destruction of foreign organisms.