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HIV‐1 gp120 signaling through TLR4 modulates innate immune activation in human macrophages and the biology of hepatic stellate cells
Author(s) -
Del Cornò Manuela,
Cappon Andrea,
Donninelli Gloria,
Varano Barbara,
Marra Fabio,
Gessani Sandra
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4a1215-534r
Subject(s) - biology , hepatic stellate cell , immunology , chemokine , immune system , tlr4 , innate immune system , proinflammatory cytokine , viremia , inflammation , human immunodeficiency virus (hiv) , endocrinology
Interaction between TLR4 and HIV‐1 gp120 in human MDM and HSC, as a novel determinant of chronic immune activation and liver fibrosis progression.