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Hematopoietic MyD88 and IL‐18 are essential for IFN‐γ–dependent restriction of type A Francisella tularensis infection
Author(s) -
Skyberg Jerod A.,
Lacey Carolyn A.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4a0517-179r
Subject(s) - francisella tularensis , biology , tularemia , haematopoiesis , myeloid , immunology , immune system , microbiology and biotechnology , intracellular parasite , cytokine , stem cell , virulence , genetics , gene
L‐18 signaling through MyD88 was essential to induce IFN‐γ and control type A F. tularensis infection.