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Myeloid‐derived suppressor cells regulate T cell and B cell responses during autoimmune disease
Author(s) -
Crook Kristen R.,
Jin Mengyao,
Weeks Michael F.,
Rampersad Rishi R.,
Baldi Robert M.,
Glekas Amy S.,
Shen Yajuan,
Esserman Denise A.,
Little Paul,
Schwartz Todd A.,
Liu Peng
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4a0314-139r
Subject(s) - myeloid derived suppressor cell , adoptive cell transfer , immunology , t cell , biology , cancer research , cell growth , b cell , autoimmune disease , cell , cancer , antibody , immune system , suppressor , genetics
M‐MDSCs inhibit autoreactive T and B cell function; reconstitution of CCR2‐deficient or wild‐type mice with M‐MDSCs ameliorates autoimmune arthritis.