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γδ T cells protect against LPS‐induced lung injury
Author(s) -
Wehrmann Fabian,
Lavelle James C.,
Collins Colm B.,
Tinega Alex N.,
Thurman Joshua M.,
Burnham Ellen L.,
Simonian Philip L.
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4a0115-017rr
Subject(s) - inflammation , alveolar macrophage , macrophage , lung , biology , immunology , t cell , tumor necrosis factor alpha , population , microbiology and biotechnology , immune system , medicine , in vitro , biochemistry , environmental health
IL4‐expressing γδ T cells decrease TNF‐α production by alveolar macrophages, reducing accumulation of M1 macrophages that promotes lung injury.