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Can we design a better anti‐cytokine therapy?
Author(s) -
Drutskaya Marina S.,
Efimov Grigory A.,
Kruglov Andrei A.,
Nedospasov Sergei A.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3ma0117-025r
Subject(s) - cytokine , biology , immunology , proinflammatory cytokine , tumor necrosis factor alpha , blockade , inflammation , receptor , biochemistry
Systemic cytokine ablation has revolutionized the treatment of autoimmune diseases; however, development of more specific and cell type‐restricted cytokine inhibitors may be feasible.