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Frontline Science: Tumor necrosis factor‐α stimulation and priming of human neutrophil granule exocytosis
Author(s) -
McLeish Kenneth R.,
Merchant Michael L.,
Creed T. Michael,
Tandon Shweta,
Barati Michelle T.,
Uriarte Silvia M.,
Ward Richard A.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3hi0716-293rr
Subject(s) - exocytosis , microbiology and biotechnology , biology , marcks , munc 18 , secretion , protein kinase c , kinase , biochemistry , vesicle , membrane , synaptic vesicle
TNF‐α stimulates exocytosis of secretory vesicles and gelatinase granules, and primes specific and azurophilic granule exocytosis that depend on p38 MAPK and actin reorganization.