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Multiple myeloma cells promote migration of bone marrow mesenchymal stem cells by altering their translation initiation
Author(s) -
Dabbah Mahmoud,
AttarSchneider Oshrat,
Zismanov Victoria,
Tartakover Matalon Shelly,
Lishner Michael,
Drucker Liat
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a1115-510rr
Subject(s) - biology , bone marrow , mesenchymal stem cell , multiple myeloma , translation (biology) , microbiology and biotechnology , stem cell , cancer research , immunology , messenger rna , genetics , gene
MM increases BM‐MSCs’ MAPKs/TI/migration in a proximity dependent and reversible manner; normal MSCs transformation by cancer cells marks this process for therapeutic targeting.