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Induction of immunomodulatory monocytes by human mesenchymal stem cell‐derived hepatocyte growth factor through ERK1/2
Author(s) -
Chen PeiMin,
Liu KoJiunn,
Hsu PeiJu,
Wei ChungFan,
Bai ChyiHuey,
Ho LingJun,
Sytwu HueyKang,
Yen B. Linju
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0513-242r
Subject(s) - biology , hepatocyte growth factor , microbiology and biotechnology , cd14 , progenitor cell , population , immunology , mesenchymal stem cell , cytokine , monocyte , t cell , stem cell , receptor , immune system , medicine , biochemistry , environmental health
IL‐10‐producing CD14 + immunomodulatory monocytes are induced through human MSC‐secreted HGF via ERK1/2 to modulate allogeneic T cell function.