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IL‐27 enhances LPS‐induced IL‐1β in human monocytes and murine macrophages
Author(s) -
Petes Carlene,
Wynick Christopher,
Guzzo Christina,
Mehta Divya,
Logan Sarah,
Banfield Bruce W.,
Basta Sameh,
Cooper Andrea,
Gee Katrina
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0316-098r
Subject(s) - inflammasome , microbiology and biotechnology , tlr4 , biology , secretion , proinflammatory cytokine , innate immune system , inflammation , acquired immune system , cytokine , intracellular , signal transduction , immunology , immune system , biochemistry
A previously undefined role for IL‐27 in the optimal production of caspase‐1‐ and P2X7‐dependent LPS‐induced IL‐1β production in monocytic cells.