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The TGF‐β‐inducible miR‐23a cluster attenuates IFN‐γ levels and antigen‐specific cytotoxicity in human CD8 + T cells
Author(s) -
Chandran P. Anoop,
Keller Andreas,
Weinmann Lasse,
Adel Seida Ahmed,
Braun Matthias,
Andreev Katerina,
Fischer Birgitt,
Horn Evi,
Schwinn Stefanie,
Junker Markus,
Houben Roland,
Dombrowski Yvonne,
Dietl Johannes,
Finotto Susetta,
Wölfl Matthias,
Meister Gunter,
Wischhusen Jörg
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0114-025r
Subject(s) - biology , cytotoxic t cell , degranulation , cd8 , microbiology and biotechnology , cd28 , microrna , il 2 receptor , cytokine , t cell , antigen , immune system , receptor , immunology , gene , biochemistry , in vitro
The TGF‐β‐inducible miR‐23a cluster attenuates IFN‐γ production and antigen specific cytotoxicity, and fine‐tunes CD8+ T cell effector functions.

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