Premium
MEK‐independent ERK activation in human neutrophils and its impact on functional responses
Author(s) -
Simard Francois A.,
Cloutier Alexandre,
Ear Thornin,
Vardhan Harsh,
McDonald Patrick P.
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2ma1214-599r
Subject(s) - mapk/erk pathway , microbiology and biotechnology , biology , protein kinase a , mitogen activated protein kinase kinase , kinase , ribosomal s6 kinase , mek inhibitor , cancer research , signal transduction , p70 s6 kinase 1 , protein kinase b
Therapeutic strategies based on MEK inhibition may require complementation of ERK inhibition in chronic inflammatory conditions featuring a strong neutrophilic component.