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Expression of Lewis‐a glycans on polymorphonuclear leukocytes augments function by increasing transmigration
Author(s) -
Brazil Jennifer C.,
Sumagin Ronen,
Stowell Sean R.,
Lee Goo,
Louis Nancy A.,
Cummings Richard D.,
Parkos Charles A.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1ma0117-013r
Subject(s) - glycan , fucosylation , sialyl lewis x , fucosyltransferase , biology , glycobiology , microbiology and biotechnology , epitope , function (biology) , inflammation , immunology , biochemistry , selectin , gene , antigen , glycoprotein
PMN‐expressed Le a represents a novel glycan target for modulation of PMN trafficking to mucosal tissues during inflammation.