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Substance P–mediated chemokine production promotes monocyte migration
Author(s) -
Spitsin Sergei,
Meshki John,
Winters Angela,
Tuluc Florin,
Benton Tami D.,
Douglas Steven D.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1ab0416-188rr
Subject(s) - biology , chemokine , monocyte , ccr2 , microbiology and biotechnology , substance p , immunology , chemokine receptor , ccl17 , immune system , receptor , biochemistry , neuropeptide
Exposure of human PBMC to substance P results in production of chemokines, including MCP‐1, which increases migration of human monocytes.