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HS1 deficiency impairs neutrophil recruitment in vivo and activation of the small GTPases Rac1 and Rap1
Author(s) -
Latasiewicz Joanna,
Artz Annette,
Jing Ding,
Blanco Mariana Pacheco,
Currie Silke M.,
Avila Martha Velázquez,
Schnoor Michael,
Vestweber Dietmar
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1a0416-195r
Subject(s) - biology , rac1 , gtpase , in vivo , microbiology and biotechnology , rap1 , genetics , signal transduction
The actin‐binding protein HS1 in neutrophils is required for chemokine‐induced activation of Rac1 and Rap1 supporting adhesion to endothelium and diapedesis in vivo.