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Interleukin‐7 promotes human regulatory T cell development at the CD4 + CD8 + double‐positive thymocyte stage
Author(s) -
Tuulasvaara Anni,
Vanhanen Reetta,
Baldauf HannaMari,
Puntila Juha,
Arstila T. Petteri
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1a0415-164r
Subject(s) - foxp3 , thymocyte , biology , interleukin 7 receptor , cd8 , microbiology and biotechnology , t cell , regulatory t cell , immunology , il 2 receptor , immune system
IL‐7 promotes regulatory T cell development in the human thymus by inhibiting apoptosis and enhancing emergence of the regulatory phenotype.