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PI3K/Akt regulates survival during differentiation of human macrophages by maintaining NF‐κB‐dependent expression of antiapoptotic Bcl‐xL
Author(s) -
Busca Aurelia,
Saxena Mansi,
Iqbal Salma,
Angel Jonathan,
Kumar Ashok
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1a0414-212r
Subject(s) - protein kinase b , pi3k/akt/mtor pathway , biology , microbiology and biotechnology , apoptosis , bcl xl , cellular differentiation , cancer research , signal transduction , programmed cell death , biochemistry , gene
Survival of macrophages is distinctly regulated during and after differentiation.