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Specific phenotype and function of CD56‐expressing innate immune cell subsets in human thymus
Author(s) -
Gerstner Stephanie,
Köhler Wolfgang,
Heidkamp Gordon,
Purbojo Ariawan,
Uchida Shizuka,
Ekici Arif B.,
Heger Lukas,
LuetkeEversloh Merlin,
Schubert Ralf,
Bader Peter,
Klingebiel Thomas,
Koehl Ulrike,
Mackensen Andreas,
Romagnani Chiara,
Cesnjevar Robert,
Dudziak Diana,
Ullrich Evelyn
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1a0116-038r
Subject(s) - biology , innate lymphoid cell , nkg2d , interleukin 7 receptor , interleukin 21 , immunology , innate immune system , immune system , cd3 , microbiology and biotechnology , population , natural killer t cell , natural killer cell , cytotoxic t cell , t cell , il 2 receptor , cd8 , in vitro , medicine , biochemistry , environmental health
Human thymic tissues show two Eomes + CD56 dim subsets, with one population resembling conventional cytotoxic NK cells, and another representing a novel non‐canonical NK cell subset.