Open AccessMultiple drug hypersensitivity associated with severe cutaneous adverse reaction
Author(s) -
Lin Choo Karen Jui,
Pang Shiu Ming,
Lee Haur Yueh
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s3-p135
Subject(s) - medicine , antibiotics , drug , penicillin , drug allergy , allopurinol , exanthem , dermatology , allergy , concomitant , adverse effect , pharmacology , immunology , biology , microbiology and biotechnology
Background Multiple Drug Hypersensitivity (MDH) was first described by Sullivan et al in 1989 as drug allergies to two or more chemically different drugs proven by in-vivo or in-vitro testing. Pichler et al added to this description by suggesting that there are two subtypes of MDH: one where sensitisation to different drug classes may occur simultaneously; the other, sequentially sometimes even years apart.