
A Novel Platelet-Targeting Fibrinolytic Strategy: Endocytosed Urokinase By Megakaryocytes Is Stored in α-Granules and Is Functional In Vivo in a Murine Model of Thrombosis
Author(s) -
Hyun-Sook Ahn,
John Tkaczynski,
Khalil Bdeir,
Victoria Stepanova,
Douglas B. Cines,
Mortimer Poncz,
С. В. Зайцев
Publication year - 2019
Publication title -
blood
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.515
H-Index - 465
eISSN - 1528-0020
pISSN - 0006-4971
DOI - 10.1182/blood-2019-124501
Subject(s) - platelet , thrombin , in vivo , plasminogen activator , fibrinolysis , urokinase , platelet activation , chemistry , immunology , cancer research , microbiology and biotechnology , pharmacology , medicine , biology