
MRI brain volume loss, lesion burden, and clinical outcome in secondary progressive multiple sclerosis
Author(s) -
Marcus Koch,
Jop Mostert,
Pavle Repovic,
James D. Bowen,
Eva Strijbis,
Bernard M. J. Uitdehaag,
Gary Cutter
Publication year - 2021
Publication title -
multiple sclerosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.729
H-Index - 131
eISSN - 1477-0970
pISSN - 1352-4585
DOI - 10.1177/13524585211031801
Subject(s) - multiple sclerosis , expanded disability status scale , magnetic resonance imaging , medicine , logistic regression , brain size , physical medicine and rehabilitation , neuroimaging , physical therapy , psychology , radiology , psychiatry
Magnetic resonance imaging (MRI) of brain volume measures are widely used outcomes in secondary progressive multiple sclerosis (SPMS), but it is unclear whether they are associated with physical and cognitive disability.