HbA1c and hypoglycaemia in intensively treated type 2 diabetes: a retrospective cohort study in primary care | Zendy

Manil Malawana | Zendy; Sally Kerry | Zendy; Rohini Mathur | Zendy; John Robson | Zendy

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HbA1c and hypoglycaemia in intensively treated type 2 diabetes: a retrospective cohort study in primary care

Author(s) -

Manil Malawana,

Sally Kerry,

Rohini Mathur,

John Robson

Publication year - 2018

Publication title -

jrsm open

Language(s) - English

Resource type - Journals

ISSN - 2054-2704

DOI - 10.1177/2054270418773669

Subject(s) - medicine , type 2 diabetes , retrospective cohort study , diabetes mellitus , hazard ratio , cohort , insulin , proportional hazards model , endocrinology , confidence interval

HbA1c below 53 mmol/mol was associated with episodes of clinical hypoglycaemia among people with type 2 diabetes prescribed sulphonylureas, and all-cause mortality in those prescribed insulins and sulphonylureas. These findings support the need for reviewing glycaemic targets and the intensities of treatment in those with low HbA1c prescribed insulins or sulphonylureas to reduce the risk of hypoglycaemia.

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