Open AccessChemical and Biological Studies of the Essential Oils of Micromelum hirsutum
Author(s) -
Pham Thi Minh Diep,
Agata Pawłowska,
Pier Luigi Cioni,
Đỗ Hữu Nghị,
Lê Mai Hương,
Châu Văn Minh,
Alessandra Braca
Publication year - 2007
Publication title -
natural product communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.221
H-Index - 44
eISSN - 1934-578X
pISSN - 1555-9475
DOI - 10.1177/1934578x0700200614
Subject(s) - essential oil , antimicrobial , rutaceae , chemistry , botany , biology , traditional medicine , food science , organic chemistry , medicine
Essential oils of the branches and leaves, flowers, and fruits of Micromelum hirsutum (Rutaceae) collected in Vietnam were investigated. Essential oils were obtained by hydrodistillation and analyzed by GC and GC/MS techniques. Essential oils yields were 0.07%, 0.125%, and 0.22% (w/w), respectively, and in each oil 43, 49, and 37 components were identified, comprising 86.0, 86.3, and 96.4% of the total amount, respectively. All the essential oils were screened for antimicrobial activity, showing positive results against various strains of bacteria and fungi. The essential oil of the flowers was also found to have cytotoxic effect against three cancer lines by in vitro assay.
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