Impact of Different Fat Depots on Insulin Sensitivity: Predominant Role of Liver Fat | Zendy

Kerstin Kirchhoff | Zendy; Kοnstantinos Kantartzis | Zendy; Jürgen Machann | Zendy; Fritz Schick | Zendy; Claus Thamer | Zendy; Fausto Machicao | Zendy; Andreas Fritsche | Zendy; HansUlrich Häring | Zendy; Norbert Stefan | Zendy

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Impact of Different Fat Depots on Insulin Sensitivity: Predominant Role of Liver Fat

Author(s) -

Kerstin Kirchhoff,

Kοnstantinos Kantartzis,

Jürgen Machann,

Fritz Schick,

Claus Thamer,

Fausto Machicao,

Andreas Fritsche,

HansUlrich Häring,

Norbert Stefan

Publication year - 2007

Publication title -

journal of diabetes science and technology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.039

H-Index - 75

eISSN - 1932-3107

pISSN - 1932-2968

DOI - 10.1177/193229680700100521

Subject(s) - insulin sensitivity , insulin , insulin resistance , medicine , diabetes mellitus , endocrinology

Overall obesity and, as it is increasingly appreciated, body fat distribution and ectopic fat deposition in liver and skeletal muscle, determine insulin resistance in humans. However, little is known about the independence of these relationships. Therefore, we determined the impact of different fat depots as well as fat accumulation in ectopic tissues such as liver and skeletal muscle in the prediction of insulin resistance in healthy humans.

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