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Human Apolipoprotein A-II Protects Against Diet-Induced Atherosclerosis in Transgenic Rabbits
Author(s) -
Yao Wang,
Manabu Niimi,
Kazutoshi Nishijima,
Ahmed Bilal Waqar,
Ying Yu,
Tomonari Koike,
Shuji Kitajima,
Enqi Liu,
Tomohiro Inoue,
Masayuki Kohashi,
Yuka Keyamura,
Tomohiro Yoshikawa,
Jifeng Zhang,
Loretta Ma,
Xiaohui Zha,
Teruo Watanabe,
Yujiro Asada,
Y. Eugene Chen,
Jianglin Fan
Publication year - 2012
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.112.300445
Subject(s) - transgene , genetically modified mouse , apolipoprotein b , chemistry , medicine , biochemistry , cholesterol , gene
Apolipoprotein (apo) A-II is the second major apo of high-density lipoproteins, yet its pathophysiological roles in the development of atherosclerosis remain unknown. We aimed to examine whether apo A-II plays any role in atherogenesis and, if so, to elucidate the mechanism involved.

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