Open AccessEffect of Sitosterol on the Concentration of Serum Lipids in Patients with Coronary Atherosclerosis
Author(s) -
FLETCHER P. RILEY,
Alfred Steiner
Publication year - 1957
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.16.5.723
Subject(s) - medicine , coronary atherosclerosis , cholesterol , blood lipids , serum cholesterol , endocrinology , coronary disease , serum concentration , coronary heart disease , cardiology
The oral administration of large amounts of sitosterol to patients with coronary atherosclerosis has resulted in statistically significant decrease in serum cholesterol in one half of the trial periods. However, because of the fluctuation of the serum cholesterol that occurs in patients with coronary atherosclerosis, further study will be necessary to demonstrate that the decrease in serum cholesterol coincident with sitosterol administration is not due to the lability of the serum lipids in this group of individuals.
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