Neurohormonal Activation and the Chronic Heart Failure Syndrome in Adults With Congenital Heart Disease | Zendy

Aidan P. Bolger | Zendy; Rakesh Sharma | Zendy; Wei Li | Zendy; Marjolein F. E. Leenarts | Zendy; Paul R. Kalra | Zendy; Michael Kemp | Zendy; Andrew J.S. Coats | Zendy; Stefan D. Anker | Zendy; Michael Α. Gatzoulis | Zendy

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Neurohormonal Activation and the Chronic Heart Failure Syndrome in Adults With Congenital Heart Disease

Author(s) -

Aidan P. Bolger,

Rakesh Sharma,

Wei Li,

Marjolein F. E. Leenarts,

Paul R. Kalra,

Michael Kemp,

Andrew J.S. Coats,

Stefan D. Anker,

Michael Α. Gatzoulis

Publication year - 2002

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.0000020009.30736.3f

Subject(s) - medicine , heart failure , heart disease , atrial natriuretic peptide , asymptomatic , aldosterone , endocrinology , natriuretic peptide , brain natriuretic peptide , cardiology , norepinephrine , plasma renin activity , renin–angiotensin system , blood pressure , dopamine

Neurohormonal activation characterizes chronic heart failure, relates to outcome, and is a therapeutic target. It is not known whether a similar pattern of neurohormonal activation exists in adults with congenital heart disease and, if so, whether it relates to common measures of disease severity or whether cardiac anatomy is a better discriminant.

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