Soft Liner with antimicrobial activity

Objective: To develop a material for denture relining and assess the microbiological and mechanical properties. The proposed liner was obtained through the incorporation of nanostructured silver vanadate (AgVO3) at 0, 1, 2.5, 5, and 10% polyethyl methacrylate (PEMA) containing plasticizer. Methods: Antimicrobial efficacy was evaluated by the Kirby Bauer agar method against Enterococcus faecalis, Pseudomonas aeruginosa, Candida albicans and Staphyloccocus aureus (n = 5); and mechanical properties were also assessed through roughness, such as Shore A hardness and tensile test. The results were analyzed by ANOVA and Tukey’s Multiple Comparison test (α = 0.05). Results: The material with AgVO3 at concentrations of 1% and 2.5% showed antimicrobial activity for E. faecalis, and 5% and 10% groups were effective for E. faecalis, P. aeruginosa and C. albicans. In the 5% group, hardness remained unchanged (p 0.05). Conclusion: Obtaining the material with antimicrobial potential promoted efficacy against E. faecalis, P. aeruginosa and C. albicans, kept the roughness property unchanged, did not change the adhesion property of the material to polymethyl methacrylate, and it maintained the hardness values compatible with resilient denture liners.