Open AccessОБГРУНТУВАННЯ ФАРМАКОКІНЕТИЧНИХ ПОКАЗНИКІВ ЛІКАРСЬКИХ ПЛІВОК ДЛЯ ЗАДАЧ МАТЕМАТИЧНОГО МОДЕЛЮВАННЯ
Author(s) -
І. М. Tymchenko,
Л. Л. Давтян,
І. О. Власенко,
S. S. Yeroshenko,
L. Yu. Babintseva
Publication year - 2012
Publication title -
medična ìnformatika ta ìnženerìâ
Language(s) - English
Resource type - Journals
eISSN - 1997-7468
pISSN - 1996-1960
DOI - 10.11603/mie.1996-1960.2011.1.48
Subject(s) - pharmacokinetics , penetration (warfare) , biomedical engineering , in vivo , pharmacology , traditional medicine , materials science , medicine , engineering , biology , microbiology and biotechnology , operations research
The search of indices is conducted for creation of model at the pharmacokinetic study of medicinal means.By methods of in vivo with the use of a single-chamber model, pharmacokinetic research has been carried out of the medicinal films containing metronidazole. It has been established, that films have a local effect because at the moment the flow of extrication of the substances from the films is greater than a penetration flow through natural biological barriers of an organism.