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THE INDICES OF CELLULAR IMMUNITY IN RATS WITH MODULATED TOXIC INJURY BY CADMIUM AND LEAD SALTS
Author(s) -
Іnna Krynytska,
H. H. Habor,
M. V. Kyryliv,
І. Р. Бекус,
Т. Ya. Yaroshenko
Publication year - 2016
Publication title -
medical and clinical chemistry
Language(s) - English
Resource type - Journals
eISSN - 2414-9934
pISSN - 2410-681X
DOI - 10.11603/mcch.2410-681x.2016.v0.i2.6676
Subject(s) - cadmium , immunity , cellular immunity , lymphocytopenia , immunology , chemistry , immune system , biology , lymphocyte , organic chemistry
In experiments on rats with modulated toxic injury by cadmium and lead salts the changes in the indices of cellular immunity in blood were studied. Results of the investigation indicate a pronounced imbalance of blood cellular immunity in the form of T-lymphocytopenia, imbalance subpopulation of T-lymphocytes with a predominant decreasing in T-supressor cells, increasing the immunoregulatory index and change in the amount of total B-lymphocytes. The most significant inhibition of cellular immunity experienced rats with combined injury by heavy metal salts.

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