Evaluation of Ultrasmall Superparamagnetic Iron Oxide-Enhanced MRI of Carotid Atherosclerosis to Assess Risk of Cerebrovascular and Cardiovascular Events: Follow-Up of the ATHEROMA Trial
Author(s) -
Andrew J. Degnan,
Andrew J. Patterson,
Tjun Yip Tang,
Simon Howarth,
Jonathan H. Gillard
Publication year - 2012
Publication title -
cerebrovascular diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.221
H-Index - 104
eISSN - 1421-9786
pISSN - 1015-9770
DOI - 10.1159/000339984
Subject(s) - medicine , atheroma , magnetic resonance imaging , stroke (engine) , cardiology , intima media thickness , carotid arteries , radiology , mechanical engineering , engineering
moderate carotid stenosis. The study randomly assigned patients into two treatment arms, low(10 mg) and high-dose (80 mg) atorvastatin therapy, over 12 weeks, and assessed the dose-response interaction [10] . The purpose of this preliminary evaluation of long-term follow-up is to report on the ability of initial USPIO-enhanced MRI to predict subsequent cerebrovascular and cardiovascular morbidity and mortality.
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