Open AccessDistinct Profiles for Mitochondrial t-RNAs and Small Nucleolar RNAs in Locally Invasive and Metastatic Colorectal Cancer
Author(s) -
Lai Xu,
Joseph M. Ziegelbauer,
Rong Wang,
Wells W. Wu,
RongFong Shen,
Hartmut Juhl,
Yaqin Zhang,
Amy S. Rosenberg
Publication year - 2015
Publication title -
clinical cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.427
H-Index - 324
eISSN - 1557-3265
pISSN - 1078-0432
DOI - 10.1158/1078-0432.ccr-15-0737
Subject(s) - colorectal cancer , small nucleolar rna , biology , metastasis , cancer research , lymphovascular invasion , cancer , carcinoma , tumor progression , pathology , microrna , oncology , medicine , non coding rna , gene , biochemistry
To gain insight into factors involved in tumor progression and metastasis, we examined the role of noncoding RNAs in the biologic characteristics of colorectal carcinoma, in paired samples of tumor together with normal mucosa from the same colorectal carcinoma patient. The tumor and healthy tissue samples were collected and stored under stringent conditions, thereby minimizing warm ischemic time.
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