CCL22 Recruits CD4-positive CD25-positive Regulatory T Cells into Malignant Pleural Effusion
Author(s) -
Xuejun Qin,
HuanZhong Shi,
Jingmin Deng,
Qiuli Liang,
Jing Jiang,
Zhijian Ye
Publication year - 2009
Publication title -
clinical cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.427
H-Index - 324
eISSN - 1557-3265
pISSN - 1078-0432
DOI - 10.1158/1078-0432.ccr-08-2641
Subject(s) - medicine , ccl17 , ccl22 , pleural effusion , malignant pleural effusion , chemokine , regulatory t cell , il 2 receptor , pleural disease , lung cancer , foxp3 , cancer research , immunology , pathology , inflammation , t cell , lung , respiratory disease , immune system , chemokine receptor
The aim of this study was to explore the presence of the chemokines CCL22 and CCL17 in malignant pleural effusion, and the chemoattractant activity of these chemokines on CD4-positive CD25-positive Foxp3-positive regulatory T cells infiltrating into the pleural space.
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