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Copper (II) Acylhydrazinates. Their Synthesis and Characterization
Author(s) -
Zahid H. Chohan,
Mehrin Farooq,
Claudiu T. Supuran
Publication year - 2000
Publication title -
metal-based drugs
Language(s) - English
Resource type - Journals
ISSN - 0793-0291
DOI - 10.1155/mbd.2001.171
Subject(s) - schiff base , copper , chemistry , escherichia coli , metal , ligand (biochemistry) , pseudomonas aeruginosa , antibacterial activity , staphylococcus aureus , characterization (materials science) , ion , metal ions in aqueous solution , stereochemistry , polymer chemistry , bacteria , organic chemistry , materials science , biochemistry , biology , nanotechnology , genetics , receptor , gene
Acylhydrazine derived furanyl and thienyl Schiff bases and their Cu(II) complexes have been prepared and characterized on the basis of their physical, spectral and analytical data. The preferred enolic form of the Schiff base function as a tetradentate ligand during coordination to the metal ion yielding a square planar complex. The Schiff bases and their complexes with different anions were tested for their antibacterial activity against bacterial species such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa andKlebsiella pneumonae.

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